Nicotinamide has long been associated with neuronal development and the survival and function of the central nervous system. The areas of greatest improvement have shown to be in joint flexibility, muscle coordination and heart mental health.
NADH (Nicotinamide adenine dinucleotide plus hydrogen) is a stable and bioavailable coenzyme that helps promote cellular energy production, and provides nutritional neurotransmitter support.
Suggested Nutritional Support Uses:
- Correct mitochondrial dysfunction
- Improve energy levels
- Improve brain function
Resveratrol is a plant compound that acts like an antioxidant. The top food sources include red wine, grapes, cranberries, blueberries, chocolate, pistachios and peanuts. Research has shown that high doses may help reduce blood pressure. Systolic blood pressure typically goes up with age, as arteries stiffen. Resveratrol may improve blood-pressure by helping to produce more nitric oxide, causing blood vessels to relax and be more flexible.
Resveratrol studies have shown improved cholesterol levels by reducing the effect of an enzyme that controls cholesterol production. Oxidation is a normal body process and very damaging to the buildup of fatty plaques on arterial walls making them much more volatile.
The antioxidant and anti-inflammatory effect may protect brain cells from damage. It has also shown to increase insulin sensitivity and prevent further complications associated with diabetes by helping to metabolise glucose and keeping blood sugar levels low.
P5P is an essential nutrient of energy metabolism within the cell and helps improve overall energy. Daily chronic fatigue and lethargy are common health complaints and P-5-P being a water-soluble vitamin may be insufficient. Diet and nutrition play a direct role in maintaining energy and an increase in neuronal health. This is partly due to P5P’s ability to improve signaling between brain cells which could explain the improvement in mental motivation. This may result in more focus, better mood, and improved motivation to carry out your daily tasks. It has been an area of research in aging and a vitamin along with vitamin B3 (NADH) which are essential for neurons and their survival. The overall neuroprotection capabilities likely play a role in overall brain health.
A lack of P5P (and vitamin B6 in general) is often found alongside high homocysteine levels which raises cardiovascular risk and can adversely affect brain health in patients.
If you are looking to just be more focused or get some more motivation, P5P may prove effective in reaching that goal.